Cancer -- New Natural Remedies!

Induction of Apoptosis to Prevent and Kill Cancer

All of the cells in our body are subject to a process called "apoptosis" -- programmed cell death. It is supposed to be triggered if the cell malfunctions, but as it's controlled by the cell's mitochondria (energy organelles), and these are largely shut down in cancer cells, cancer usually escapes apoptosis.

A few years ago, a simple substance -- dichloroacetate -- was found by a researcher in a Canadian university which restores apoptosis in cancer cells. He transplanted about ten human cancers into animals, gave them dichloroacetate, and it killed all the tumors without harming the animals. It's a simple substance, just vinegar acid with two chlorine atoms added. It's the most effective and harmless anticancer treatment ever found. However, since the substance is simple and has been in use for years for other purposes, it isn't patentable, so pharmaceutical companies have no interest in it. You can buy it from various people on the Internet if the FDA has not shut them down. Look for "DCA" or "dichloroacetate". DCA has a small degree of toxicity, which is discussed on the various websites. It can be reduced by taking certain nutrients.

There are also some nutrients that have been found which themselves restore apoptosis in cancer cells, and these can be bought in health-food stores. Unlike DCA, they have no toxicity.

Here are seven natural apoptosis promoters:

Co-Q10
curcumin
ellagic acid
Se-methylselenocysteine aka methylselenocysteine
grapeseed extract
capsaicin
U-Fucoidan/Modifilan/Laminaria japonica/konbu

The first six substances are sold in most healthfood stores.


Here is a news report on DCA:
News Video on Dichloroacetate

Here is a scientific paper explaining exactly how DCA works:

Metabolic Targeting As An Anticancer Strategy (pdf)





Modifilan can be obtained from this company: modifilan-seaweed-extract.com
in the U.S. and Canada. For additional distributors or other information, contact this company: MODIFILAN.COM

It's probably most effective to use several (or all) of them to fight cancer. However, there could be a possibility of activating apoptosis in non-cancerous cells by doing that, since they are not known to be non-toxic when used in combination. I found this in a medical dictionary:

"When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer, Huntington and Parkinson diseases."

Another natural cancer remedy is graviola fruit. However, the ingestion of it for a long time is associated with a type of Parkinsonism. One of the substances in it fights cancer by inducing apoptosis. See references 9 and 23 on this page:

http://usefulmedinfo.com/1-disease-groups/metabolic/3-cancer/prostrate/graviola.htm

On the other hand, Co-Q10 is already found in every cell of the body (and diminishes as we get older, so needs supplementation), while curcumin (curry spice), ellagic acid (from pomegranates and other fruits), methylselenocysteine (found in garlic and broccoli), grapeseed extract, and capsaicin (the "hot" substance in red pepper), are all foods.

So, taking 3 or 4 of the six, chosen on a rotating basis, and in the recommended amounts, to prevent a recurrence of cancer (metastasis) after surgery, may be a lot safer than not doing so, and may well be less toxic than the cancer chemotherapy drugs used for the same purpose. Vitamin D-3, about 10,000 IU/day, is also very good for cancer prevention. Personally, I've been taking 400 mg. of Co-Q10, 75 mg. of grapeseed extract, and 400-600ug (I'm a big guy) of selenium as methylselenocysteine for years, for general health reasons.

Thus, proceed at your own risk. Someone should feed large amounts of all of these substances simultaneously to some rats for a while and then check them for loss of brain or other cells.


The information I have on these substances needs more organizing, but since I promised some people in a hospital waiting-room that I'd put it on my website, here is the current (messy) state of my Firefox bookmarks on the subject. I'll be fixing this up and adding to it in the future.

Cancer, Apoptosis and its inducers - DCA, ellagic, capsaicin,

Apoptosis

Apoptosis - Wikipedia, the free encyclopedia
Caspase - Wikipedia, the free encyclopedia
Apoptosome - Wikipedia, the free encyclopedia
Cellular respiration - Wikipedia, the free encyclopedia
p53 - Wikipedia, the free encyclopedia
History and highlights in apoptosis research - Wikipedia, the free encyclopedia
Cysteine protease - Wikipedia, the free encyclopedia

Mitochondria

Mitochondrion - Wikipedia, the free encyclopedia
Mitochondrial matrix - Wikipedia, the free encyclopedia
Cytochrome c - Wikipedia, the free encyclopedia
Electron transport chain - Wikipedia, the free encyclopedia
Coenzyme Q10 - Wikipedia, the free encyclopedia
Citric acid cycle - Wikipedia, the free encyclopedia
Proton pump - Wikipedia, the free encyclopedia

Apoptosis Promoters

Apoptosis New

"brown seaweed" cancer - Google Search
Seaweed
modifilan - Google Search
Le Magazine, February 2006 - As We See It: Coq10 And Cancer
site:www.lef.org CoQ10 apoptosis - Google Search
Coenzyme q10 prevents apoptosis by inhibiting mito...[J Biol Chem. 2003] - PubMed Result
BiomedExperts: Coenzyme Q protects cells against serum withdrawal-induced apoptosis by inhibition of ceramide release and caspase-3 activation.
Cancer Forums - Melanoma and Skin Cancer Forum - Does CoQ10 Induce Melanoma Apoptosis & Inhibit Mel Mets?
Breast Cancer Choices Supplement Strategies: CoQ10
Natural Health Research Institute » CoQ10 May Provide Energy Needed to Boost Effectiveness of Anti-Melanoma Treatment after Surgery
Le Magazine, February 2006 - Abstracts: Coq10, Antioxidants, Blueberry, Rhodiola, And Vinpocetine
Le Magazine, June 2001 - Report: An Unjustified Attack On Vitamin E
Le Magazine, June 2001 - Report: An Unjustified Attack On Vitamin E
Le Magazine, February 2006 - Abstracts: Coq10, Antioxidants, Blueberry, Rhodiola, And Vinpocetine
Le Magazine, February 2006 - Abstracts: Coq10, Antioxidants, Blueberry, Rhodiola, And Vinpocetine
Le Magazine, February 2003 - Abstracts: Eye Health, Coq10/Parkinson's, Cancer/Vitamins, Chlorophyllin, Nutrients
Le Magazine, October 2001 - Abstracts: Theanine, Coq10, Green Tea/Cancer, Micronutrients

Se-methylselenocysteine

Breast Cancer Research | Full text | Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro
Se-Methylselenocysteine induces apoptosis through caspase activation in HL-60 cells -- Kim et al. 22 (4): 559 -- Carcinogenesis
Se-methylselenocysteine - Google Search
SE-METHYLSELENOCYSTEINE - Best Selenium - 200 Caps

Dichloroacetate

Metabolic Targeting As An Anticancer Strategy (pdf)
dichloroacetate - Google Search
Dichloroacetate.org - Index
Dichloroacetate.org - Index
Alternative to dichloroacetate
Alternative to dichloroacetate

buydca.com

About BuyDCA Quality - Sodium Dichloroacetate - Cancer Treatment for Pets
Buy DCA - DCA Sodium Dichloroacetate. The Purest & Lowest Price Pharmaceutical Grade DCA (99+% Pure)
BuyDCA.com offering the purest and lowest priced DCA Sodium Dichloroacetate and Potassium Dichloroacetate available.
Buy DCA - DCA Sodium Dichloroacetate. The Purest & Lowest Price Pharmaceutical Grade DCA (99+% Pure)
BuyDCA.com offering the purest and lowest priced DCA Sodium Dichloroacetate and Potassium Dichloroacetate available.
BuyDCA - Sodium Dichloroacetate Online Store
The Purest & Lowest Priced Pharmaceutical Quality DCA (Sodium Dichloroacetate). Buy Sodium Dichloracetate or Potassium Dichloracetate online in 20 gram, 50 gram, or 100 gram bottles.
DCA Dichloroacetic Acid FAQs - Cancer Treatment for Pets

thedcasite.com

Tributyrin - a possible synergist of dichloroacetate
DCA and Caffeine Protocol - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate
DCA, tea and cancer - DCA and Black Tea - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate
DCA Dosage - The DCA Site - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate
DCA-based Protocols
TM - Tetrathiomolybdate - The DCA Site - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate
DCA Discussion Forum
DCA Discussion Forum - newspaper article
newspaper article
DCA Discussion Forum - A good source of DCA
A good source of DCA
The DCA Site - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate

physorg

By amplifying cell death signals, scientists make precancerous cells self-destruct
PhysOrg.com: When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the signals that tell these precancerous cells to die. The trick: Inactivating a protein that normally helps cells to avoid self-destruction.
Synthetic Molecules Could Add Spice To Fight Against Cancer
PhysOrg.com: Seeking to improve on nature, scientists used a spice-based compound as a starting point and developed synthetic molecules that, in lab settings, are able to kill cancer cells and stop the cells from spreading. The researchers are combining organic chemistry, computer-aided design and molecular biology techniques in developing and testing pharmaceutical compounds that can fight breast and prostate cancer cells. The synthetic molecules are derived from curcumin, a naturally occurring compound found in the spice turmeric.
Key to Treating Cancer May Be Finding its Original Cell
PhysOrg.com: (PhysOrg.com) -- Cancer biologists are turning their attention to the normal cells that give rise to cancers, to learn more about how tumor growth might be stopped at the earliest opportunity.
Researchers discover how tumor suppressor inhibits cell growth
PhysOrg.com: Genes that inhibit the spontaneous development of cancer are called tumor suppressor genes. One of the major tumor suppressors is p53, a protein that acts in the cell nucleus to control the expression of other genes whose products can inhibit cell proliferation (increase in cell number) and cell growth (increase in cell size). Abnormal cell proliferation and growth are characteristics of cancer. Scientists previously knew which p53 target genes inhibit cell proliferation, but those required for inhibition of cell growth were unknown.

Dichloroacetate - RightHealth Topic Page
dichloroacetate in Herbs & Supplements such as Pyruvate, in Diseases & Causes such as Acidosis, MELAS,
"dichloroacetic acid" synthesis - Google Search
347795 Sodium dichloroacetate 98%
Specification Sheet
Medicor Cancer Centres - DCA Therapy
Medicor Cancer Centres will be accepting patients for DCA (Dichloroacetate) Therapy.
Medicor Cancer Centres - ChemoFitâ„¢
Medicor Cancer Centres welcomes you.
Pharmacy ordered to stop selling compound
The online source for Edmonton news, business, sports, entertainment, classified ads, horoscopes, weather, local news and more.
Clarkson Price lists
dichloroacetate - Google Search
Dichloroacetic acid - Wikipedia, the free encyclopedia
Dichloroacetic acid - Wikipedia, the free encyclopedia
Treat-Cancer.nl - Treat Cancer with Flavonoids - no Chemotherapy side effects - Cancer Treatment
Official University of Alberta DCA Site
Cheap, safe drug kills most cancers - health - 17 January 2007 - New Scientist
Dichloroacetate causes toxic neuropathy
ABC News: DCA: Cancer Breakthrough or Urban Legend?
Dichloroacetic Acid, Reagent - D - Alphabetical Listing of Chemicals * 79-43-6
Clarkson Laboratory & Supply Home Page

CoQ10

DCA

synthesis of dichloroacetate - Google Search
DCA Dosage - The DCA Site - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate
About BuyDCA Quality - Sodium Dichloroacetate - Cancer Treatment for Pets
Contact BuyDCA.com
BuyDCA.com order
DCA Dichloroacetic Acid FAQs
About BuyDCA Quality - Sodium Dichloroacetate - Cancer Treatment for Pets
dca canada - Google Search
Cancer therapy: When all else fails - health - 28 March 2007 - New Scientist
The DCA Site - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate
BetterDCA.com makes contaminated product- The DCA Site - Updating You on DCA and Cancer - Dichloroacetic acid and Dichloroacetate
Dichloroacetate (DCA): A Cure for Cancer? - Associated Content
Medicor Cancer Centres - DCA Therapy
The Michelakis paper on Cancer and Dichloroacetic acid and Dichloroacetate

Curcumin

curcumin apoptosis - Google Search
Le Magazine, August 2001 - In The News: Curcumin, Folate Acid, And Coq10

Graviola

graviola - Google Search
Graviola causes parkinsonism
/Reports/HSI/LHSIJA43/

Grape Seed Extract

Grape Seed Extract Found To Kill Leukemia Cells In Laboratory Tests
BBC - Grape extract kills cancer cells
Xianglin Shi, Ph.D. - Phone: (859) 257-4054 - E-mail: xshi5@uky.edu
"Xianglin Shi" "University of Kentucky" cancer - Google Search
Induction of Apoptosis in Human Leukemia Cells by Grape Seed Extract Occurs via Activation of c-Jun NH2-Terminal Kinase -- Gao et al. 15 (1): 140 -- Clinical Cancer Research
"Induction of Apoptosis in Human Leukemia Cells by Grape Seed Extract" - Google Search

Modifilan - U-Fucoidan- Laminaria Japonica - Konbu

Modifilan, body detox, thyroid conditions, weight loss, healthy intestinal tract

Tumor lysis syndrome - Wikipedia, the free encyclopedia
Infection-mimicking materials to program dendritic cells : in situ : Abstract : Nature Materials
Implant raises cellular army to attack cancer - tech - 11 January 2009 - New Scientist
Dr. James Howenstine -- Use Of CoQ10 To Treat Malignancies
New Oral Angiogenesis Inhibitor Offers Potential Nontoxic Therapy For A Wide Range Of Cancers
Apoptosis - Wikipedia, the free encyclopedia
p53 - Wikipedia, the free encyclopedia
Caspase - Wikipedia, the free encyclopedia
Ellagic acid stimulates apoptosis - Wikipedia
ELLAGICA
USP grade ellagic acid combined with nattokinase, gingko biloba and pumpkin extract for all the benefits of ellagic acid without the increased blood coagulation that ellagic acid alone can trigger.
Anti Cancer Ellagic Acid
Capsaicin stimulates apoptosis
Fungus Causing Cancer -- A Novel Approach to the Most Common Form of Death - Articles
Gc-MAF -- Cancer Cured For Good